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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943186d2e822f21f98d0bb7e9e20fc0ea301efeb30bd15c2410925a50f340d11' 
  AND token = '9uLcn4yXMi8v1fwNcdWpMZprGarTcYu44aEH9xvHd6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}