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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c32a7fabb3d5616b7f90d073cf4488aaf5e951bae3c9f3275884f26623048d' 
  AND token = '5fTNH3Af2FNWTHyzkTPoLgjMiSfVOZV+q65ppo6zCcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}