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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abd5c80d8278df43938b124d2237bf167287734c726516cdb58b839aa889f94f' 
  AND token = 'YpB9B4oydAxO+mqPiRaGsff/Ld/ZdrNUsT5U+/DaIAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}