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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e32845babf69d6121bc697e9be5d68b05c3b0f86158a5ac0152b02394025dfdc' 
  AND token = '2IKCJY8dbUysc1fitbidRzeBnVfjW1qAxzgzsX8aT/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}