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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745eb5738bf7b47ca4c041c26c836883f5dc389a773c7c0392925c06b565b7e6' 
  AND token = 'GhUXdmXESSohMPa1P7l614rhqUJGqwVjCinlQsoTdxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}