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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8aec488ab71607dfabc4e68595d52f665ef34cb276e70d75432ce7f0846ab67' 
  AND token = 'k4Ha6ESq6eUKsqCpFUGXWhOl/B9h0hGj6ixpW/tOoeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}