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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0182d67bc905ba3a381c60b3a2494164b012ec97df20cffb0fdd2b16de1543ca' 
  AND token = 'c3ZhOS9w4H06MNZhqAZL3BHk31+7L1vQ+Hq9W9WJdXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}