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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33581087027af535a57bc6c7cb1ac14a1a376d2a4189b599d30afdab37d26cd9' 
  AND token = 'LoeQdugtKk/Bjj1MIkP7Ln71d2h13Z1nP9JUgLUG71Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}