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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f76cf1b49c775043f2e4dbbcb30681ddd166f4d47f9dee360ec3b03d13a3d7' 
  AND token = 'sLN89O/tlyfSB+s6S6Hz2H5Ios8g3uiIy+tbnFSBxA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}