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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aca5f0a9b51490134128ddd4a13d08c9f012a01a8667fc3fe5a1b9223cdbb6c' 
  AND token = 'C163d7xr/3c5p/9dLx1EmtC4YD4PPtYqVVJc6AZSfDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}