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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f557f77d606f9d7724840d4d04eb6f767d7d274311d652849b9b9d44c2a5480' 
  AND token = 'dNOCg+o3vA0ZPAIC9oSyUKMAiqG7LDFCtahoq2Mkcrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}