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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b49e4163a41a717a130a06e2159722c2097883e2aecad3b5f73831027065c53' 
  AND token = 'jrbTYG/HdNK6hAq83qAcTdEr+QwwwD3RtXrPH+OMkc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}