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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db457ad3b1f81d0c3d1d3239198471f5365873e27e87d7426c2489d391a4b66c' 
  AND token = 'C4IjiWumDT4K1dLSfVkF5nZOZ24TLtoPQ6Xep+MAQtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}