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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea1a0a253c5776425f097db83ade48b58eb98a17ff3bc47767d05cd3b960ea39' 
  AND token = 'CbxjnrTQar2FbmJumO367IA1fV9qDmIHFdahisGem7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}