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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f6588e284f3bae45ae820b13cf04bd5de7512a5159688f054146803024263a6' 
  AND token = 'luBmCcNxh4gVH4W9quIBECir2SyHng3Uw86uKtNt4vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}