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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9507b1871ed6a7d6690f12edff77c1b34bdc64d85a2585eb9d8aecdc5d95febb' 
  AND token = 'GLPkqFe3GGJ8bLKkAMVCLP9o4rvDORrJ9PAzgEO7QG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}