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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f149a24222f53f75fa8c11bb035df1601ae9a0256b8f5450deccba8c4a1bb50' 
  AND token = 'IQN2nzYxd8VdY2K7L2MZg7OCvk7ZiN28F+A3yW349ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}