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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58aa7d87ea86cf1fbdb5b95da39f4f441ea7567f71049b1ef3197b9a83f40a64' 
  AND token = 'FR7hoAnPaSoxEO+Z1QG9I475+AKNyRSw9uRObESj47U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}