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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645048fd7f56128b0f62bbf609058e6f2cb2367c5e1f77465f442eba571458a6' 
  AND token = 'WpcrCP3tbfKIRrth0/n3XgJqtz+cPs/IwD1IFnlTTnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}