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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9efd1b871790c8f8f24c47f6712c9cad6607e80ee3d3528381b0f70951a83631' 
  AND token = '8TZuwpJyu+jP4p0KNaywrXV4rs7OB6NNcfcKd6Zq0Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}