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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dea6d46e6b43d6519deb700a20d3a1c1a8ef2cad2eff4858292ed1b703fe4eb8' 
  AND token = 'XKoRXCFp2NwCntXM+QtHxSAuBxAwIG7B4Aaa1agE8g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}