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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d5a03155144a3252c2413e405f08c57cbe884e710114073a4f1a5e5a2e57cc' 
  AND token = '0axCEMChKD25nO8EvBKeXU0h/P+ZsCyg7YQFJw93qgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}