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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e014ae8cf79d1fde945b26df7de247bb9b863dbadc9b296bb1df79c806dd28c' 
  AND token = 'EdJG7CVvB5DTaeYXM0XQXf61qE/ndjzFG5wq8RIO5CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}