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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35086b6c786f79b5e26284fcd182d301df9497bcd701e561a96a6abf7a742a3a' 
  AND token = '4ULlDE0TJDDfQg0h/m6FkyXpEN0XYNuktaePayLc9ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}