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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '024fd52f0cfdf636d5f5eed70807d8a83b00d01bd3a240d0d140ce5dd4c6d92a' 
  AND token = 'owCNWZY1JKkE0gWIPshFvT9sRLzdXHyp6KBgwYq5prw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}