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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '297018ab1fd317ef6a24acb5fc4293b3eb05858a73d9655bf85c93b89e269b39' 
  AND token = 'C3+zuXxZHM+9bT3AK4n9+4LXoSL/7ZcszYSBPZZ6PUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}