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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '942c0faa1478c3a62bba5d4865120f863b78548a9d5e858b3f1a01a0f598f1d8' 
  AND token = '/5V1hM8VhmhOe3Q1MqPBmDZ41wYqb5RceNWNUPfj5bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}