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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffc6498b3279a25d3ef89ba49685f11f433df6e6ad34ef12918b4ecc2f1cd9b' 
  AND token = '8RUtAp82IsNwb4Kp2mZA8hXtnj+8Qd9+3ZpM4udONDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}