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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d9e7410cf88bf16c09ca8de31a12cc040c59786c1808adcbe58802446f8b1b8' 
  AND token = 'kIQKOeWh0Qxx2WDuqTEMEfiqVBr+C0J2Bj4WM3fASxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}