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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72bbbdd474f322c01bb106623135db2db2caa9d7e603b2ec06aa53eb5ea7083' 
  AND token = 'YDz1vqmZBD61fE+Xzpn9DGWHr+/VlZ1UJhi7Nax3yuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}