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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c4152ad8aaf13f3f6ffd804c880661b5aad8d4cab26b5e423e61a6919e7940' 
  AND token = 'Xf0FQ+T0sTI78v1BcmHKaI0U8JCKV9SZDimJvHrZBKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}