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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14c3ee8556f0d38c751da74d0e20523c1907f799d3e2212b1c36302ba3b4e23b' 
  AND token = 'fSjqM8e5L+u0uRQZ+RBpZ4ygQKhG1xG2eur/s61wyp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}