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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f592377625e2ab69cb3bb039798a7d88dc5a4d99c3b6499211d48fb774354fe6' 
  AND token = 'SPh9W2c2bnyHnW0lvZqrCZ3EPLS4ol189/xBxOfBwkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}