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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e62209b7d501854ce87fbb4741b2d683f0fd5bf9b4532a2bdd0d011329c980af' 
  AND token = 't1R7AhAV2LHsaAUBt6JsRpumoUazwGNgbik6l6QqfH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}