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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4341f2f9e7372c0ab498e4f90d3f8b0112281909940e501613aae8ad55d61da2' 
  AND token = 'As4vGBjAZHHZI1hKlxCity9M2e7W9BF2Js0nBVJESog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}