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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab0b71f7ccfca5ee0dcb0fd8f3c58e391ea5a558e9336069b01166b417cb8985' 
  AND token = 'FUuDiyfzCGhyzZcgs2aCI0Fi6zYAiOS3XAUeL4apLeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}