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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef23d9e58bfdce9c33d2f80e4455135026516375c6e5467a13fd0f80fe88051' 
  AND token = 'wj1Zq9gt48RDLp9zhrbLWOeZAf5H53g/UdPDhXr2SNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}