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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e905132e7a0f3389f207abe0da2278556766beaf9d5aa5e88043068bc01403c7' 
  AND token = 'cXv6rcB/S40VWHk3EiFpz0TfHmuYH+HuQeIcsMXj4rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}