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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20a50f5407223a5bbca193d47fa47a6aa03668cc75953795746c6b6c14a62f0f' 
  AND token = 'hgL3PVNl/SYhxuKhu39a98ujkPa/z5MQS1NjxSKAwVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}