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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22f5cb72cb6696d2b0dfabd0616c31130891a5721c37c57566a56f2acd707cf' 
  AND token = 'o6fyrO9kA7a8/ug0yjyOMwwS9hLEbRmFVRkzAJbKP78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}