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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4da15037bee98c5e232f54b068df8b66bc46af6656735a71c0c3445ca3761f37' 
  AND token = 'pUBBrk0jIyBSMTJ25p/8PJgXTBc97W/nfJNJ/49UiOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}