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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849583993eca396c4b4987668dffd365228a23f2b553e4404f4829eb05e0bc36' 
  AND token = 'M8zW2OAo17K00hcFccYp9dOA2nSAxe249l3XQi6uves=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}