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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb8c08a03f1a4c892c8c1a659a3d5fc0cf0e2d19d514cf2a0102000300f2301' 
  AND token = 'kcJRQ3tJedu789NOORmh3bD5eySQ4xeNE4vKLcC43HA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}