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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad47d7a04b00ba52acf8987fc5a5747b292f1b1f8f8a1da8ac5aab1e35132244' 
  AND token = 'ULarQ6YC2c0Cd0fIPcIoCMNqYBEsAC4+wwHtII5vu3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}