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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfa49959551cabd58fe190a1fe49cf4fcfcb466a982fe649c9ccfcedb920c822' 
  AND token = 'jCkdLiVDzSUHFbRILjZ8QH3tT0x7Jro4b3IEyhTKyC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}