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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39db26989abceac4445e3b4dedea7fd30954a9b8b2a04a87add96b2d1c45754' 
  AND token = 'eqAf4m4NxXDWuYK2M/9DTMcmPaGvQEhJPzSysfnt9Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}