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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c21244d9ce7d1506171b3997879a00b0368b083df91404c74435d10e75d0ce4' 
  AND token = 'MALnN9nZX1k+4SplUFytL14Vwm1LmMfxtZ/VF3O3+V8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}