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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fac21772bfb7de08bd0aa3e3f31741bb5e043987c28daf9c66ab72d8beeee6e6' 
  AND token = 'UX2XEt6esjFbwloHhX89SMZNt5Q3ZwsiFNGgL5hkZFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}