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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d5c94559cdd32b7b330b0690e76ee14e22198ec3568f0f5b6d8306244cb5442' 
  AND token = 'Aia2Fp/E1XIMUKzeW+F2uM9IBtYBzMROEctQVvgqa84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}