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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3589ea10403ebb1876d67216f35f748b9f55dfb212900e7e37f1e49a414c631' 
  AND token = 'Rq5UkQ3//8trNP9MdlugvlGy6IsCGMxuKvhdPp4p628=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}